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* Our limited-time specials are ready for you to browse!! Phytobase is our Cream of the Month - including free sample formulas for you to download. *

Salt Durable Cream

SKU B-SALT500-695987

Salt Durable Cream — High-Capacity Transdermal Base

Salt Durable Cream is a cosmetically elegant compounding base built for transdermal preparations containing high percentages of APIs or multiple actives. It delivers an improved feel over traditional PLO-based delivery systems and is ready to use, requiring no pre-wetting of actives or additional thickening agents. With a high API load capacity of 40%, it gives compounders the flexibility to formulate complex, multi-drug preparations with confidence.

  • High API Load (up to 40%)
  • Paraben-Free
  • Fragrance-Free

Product Highlights

  • Broad pH Stability — Remains stable across a wide pH range, giving compounders confidence when working with a variety of active ingredients.
  • Broad Salt Stability — Maintains consistency and performance even when formulated with a wide range of salt forms.
  • No Pre-Wetting Required — A time-saving, ready-to-use base that skips the pre-wetting step traditional PLO systems require.
  • No Additional Thickener Needed — Comes fully formulated, streamlining the compounding process and reducing prep time.
  • Improved Feel vs. Traditional PLO — Offers a more cosmetically elegant, refined after-feel than conventional PLO-based delivery systems.

API Load

High (up to 40%)

Applications

  • Dermatology
  • Hospice
  • Pain
  • Veterinary

Water activity: greater than 0.6

Passes Antimicrobial Effectiveness Testing (AET) as defined by USP<51> — this base is considered to have an effective preservative system. 

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Salt Durable Cream is an off-white, homogenous, unscented cream.

  • ph: 4.5-5.5
  • Specific Gravity: 0.9 – 1.1 g/cm3
  • Viscosity: 175,000 – 450,000 cPs
  • Water activity: greater than 0.6

Ingredients

Deionised Water, Cetearyl Alcohol, Poloxamer 407, Isopropyl Palmitate, Soy Lecithin, Dimethicone, Paraffinum Liquidum, Phenyl Trimethicone, Tocopheryl Acetate, Magnesium Aluminium Silicate, Phenoxyethanol, Aloe Barbadensis Leaf Powder, Propylene Glycol (and) Diazolidinyl Urea (and) Iodopropynyl Butylcarbamate

Compatible Solvents

Alcohol, Diethylene Glycol Monoethyl Ether, Dimethyl Sulfoxide, Propylene Glycol, Purified Water