Supposibase-F Fatty Base

Supposibase-F — Fatty Acid Suppository Base

Supposibase-F is a fatty acid suppository base suitable for both rectal and vaginal use. Manufactured from raw materials of strictly vegetable origin, it forms a waxy solid with a melting point of 33.5-37°C, allowing it to remain stable at room temperature while melting readily at body temperature. Its consistent physical properties
support reliable suppository formulation across a range of mold sizes.

• Vegetable Origin
• A waxy, hard-fat suppository base that holds its shape at room temperature
• Melts consistently between 33.5–37°C, supporting reliable release at body temperature

Product Highlights

• Dual-Route Versatility — Suitable for both rectal and vaginal suppository formulations.
• Consistent Density — Maintains a density of 0.94 g/mL for predictable, reproducible formulations.
• Known Displacement Factor — An estimated displacement factor of 0.7 simplifies dosing calculations when compounding.
• Multiple Mold Compatibility — Supported by general formulas across four common mold sizes (1.3 mL, 2.0 mL, 2.25 mL and 3.0 mL).
• Simple, Vegetable-Derived Ingredient Profile — Composed of just two ingredients (hydrogenated palm kernel glycerides and hydrogenated palm oil) for a clean, predictable base.

Applications

• Rectal Use
• Vaginal Use

Water activity (aw): less than 0.6. This base is anhydrous.

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