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SaltStable LS Advanced™

by Humco
SKU 6-SALT-STABLE-Ls-697405

SaltStable LS Advanced™ – Transdermal Pain Management Cream

Salt Stable LS Advanced™ is a next-generation transdermal cream base that delivers a smooth, dry-touch finish without sacrificing performance, durability, or versatility. It supports all active ingredient classes regardless of salt form, with superior capacity for multiple APIs in one formulation. Its self-stabilising composition ensures long-term stability with no added emulsifiers required.

  • High API loads
  • Works with all actives regardless of salt form, so no reformulating needed across products.
  • No wetting or thickening agents required, and it stays stable long-term without added emulsifiers

Product Highlights

  • Versatile applications – suited for pain management, veterinary medicine and sports medicine cases
  • Broad API compatibility – 30% hydrophilic and 40% lipophilic compatibility, supporting a wide range of active types
  • High-capacity active loading – validated in vitro for up to 8 actives in one formulation, with a total API load of 40%.
  • Silogel-based formula – a silicone-based organogel delivering a smooth, dry-touch feel that's less sticky and less tacky than typical cream bases.

API Load

High (~40%)

Applications

  • Dermatology
  • Pain
  • Veterinary

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Specifications

SaltStable LS Advanced is an off-white heavy W/O cream emulsion

  • pH: 7.1 – 7.5
  • Specific Gravity: 0.9 g/mL
  • Viscosity: 800,000 – 1,200,000 cps

Ingredients

Purified water, mineral oil, ceteareth-20, cetearyl alcohol, poloxamer 407, phenyl trimethicone, magnesium aluminum silicate, C30-45 alkyl cetearyl dimethicone crosspolymer, aloe barbadensis leaf extract, dimethicone, phenoxyethanol, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, vitamin E acetate, propylene glycol, isopropyl palmitate, lecithin, diazolidinyl urea, ethylhexylglycerin, methylparaben, propylparaben

Compatible Solvents

  • Diethylene Glycol Monoethyl Ether
  • Glycerin
  • Propanediol
  • Propylene Glycol